L-ergothioneine modulates oxidative damage in the kidney and liver of rats in vivo: studies upon the profile of polyunsaturated fatty acids.

@article{Deiana2004LergothioneineMO,
  title={L-ergothioneine modulates oxidative damage in the kidney and liver of rats in vivo: studies upon the profile of polyunsaturated fatty acids.},
  author={Monica Deiana and Antonella Rosa and Viviana Casu and Rosaria Piga and M Assunta Dess{\`i} and Okezie I. Aruoma},
  journal={Clinical nutrition},
  year={2004},
  volume={23 2},
  pages={
          183-93
        }
}
BACKGROUND & AIMS L-ergothioneine is a fungal metabolite exhibiting antioxidant functions in cells. The aim of this study was to assess the effect of oral administration of L-ergothioneine on the oxidative damage in vivo caused by the Fenton reagent ferric-nitrilotriacetate. METHODS Rats were supplemented with L-ergo prior to the administration of acute dose of ferric-nitrilotriacetate. Kidney and liver levels of L-ergothioneine, glutathione, alpha-tocopherol, polyunsaturated fatty acids and… CONTINUE READING
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