L-carnitine supplementation for the management of fatigue in patients with cancer: an eastern cooperative oncology group phase III, randomized, double-blind, placebo-controlled trial.

  title={L-carnitine supplementation for the management of fatigue in patients with cancer: an eastern cooperative oncology group phase III, randomized, double-blind, placebo-controlled trial.},
  author={Ricardo Alberto Cruciani and Jenny J Zhang and Judith B. Manola and David Cella and Bilal Ansari and Michael J. Fisch},
  journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology},
  volume={30 31},
  • R. CrucianiJenny J Zhang M. Fisch
  • Published 1 November 2012
  • Medicine
  • Journal of clinical oncology : official journal of the American Society of Clinical Oncology
PURPOSE L-carnitine, a popular complementary and alternative medicine product, is used by patients with cancer for the treatment of fatigue, the most commonly reported symptom in this patient population. The purpose of this study was to determine the efficacy of L-carnitine supplementation as a treatment for fatigue in patients with cancer. PATIENTS AND METHODS In this double-blind, placebo-controlled trial, patients with invasive malignancies and fatigue were randomly assigned to either 2 g… 

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