L-carnitine inhibits ethanol-induced gastric mucosal injury in rats.

  title={L-carnitine inhibits ethanol-induced gastric mucosal injury in rats.},
  author={Dikmen Dokmeci and M. Tuğrul Akpolat and Nurettin Aydoğdu and Latife Doğanay and Fatma Nesrin Turan},
  journal={Pharmacological reports : PR},
  volume={57 4},
L-carnitine is a quaternary amine that is essential for the normal oxidation of long-chain fatty acids by mitochondria. It is known that L-carnitine and its derivatives prevent the formation of reactive oxygen species, scavenge free radicals and protect cells from peroxidative stress. Oxygen-derived free radicals and lipid peroxidation products play a critical role in the pathogenesis of ethanol-induced gastric mucosal injury. The aim of the present study was to determine the effect of L… CONTINUE READING


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Publications referenced by this paper.
Showing 1-10 of 39 references

Carnitine as a free radical scavenger in aging.

Experimental gerontology • 2001
View 4 Excerpts
Highly Influenced

Effect of carnitine on stress-induced lipid peroxidation in rat gastric mucosa

VN Izgut-Uysal, A Agac, N Derin
J Gastroenterol, • 2001
View 5 Excerpts
Highly Influenced

Carnitine metabolism and its regulation in microorganisms and mammals.

Annual review of nutrition • 1998
View 3 Excerpts
Highly Influenced

Effects of oxygen radical scavengers on the quality of gastric ulcer healing in rats.

Journal of clinical gastroenterology • 1995
View 5 Excerpts
Highly Influenced

Neuroprotective effects of FK-506, L-carnitine and azathioprine on spinal cord ischemia-reperfusion injury.

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery • 2004
View 1 Excerpt

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