L-NAME and L-arginine differentially ameliorate cigarette smoke-induced emphysema in mice.

@article{Valenca2011LNAMEAL,
  title={L-NAME and L-arginine differentially ameliorate cigarette smoke-induced emphysema in mice.},
  author={Samuel Santos Valenca and Carlos Romualdo Rueff-Barroso and Wagner Alves Pimenta and Adriana Correa Melo and Renata Tiscoski Nesi and Marco Aur{\'e}lio dos Santos Silva and Lu{\'i}s Crist{\'o}v{\~a}o Porto},
  journal={Pulmonary pharmacology & therapeutics},
  year={2011},
  volume={24 5},
  pages={587-94}
}
Nitric oxide (NO) represents one of the most important intra- and extracellular mediators and takes part in both biologic and pathologic processes. This study aimed to verify the treatment with an NO inhibitor and an NO substrate in pulmonary emphysema induced by cigarette smoke (CS) in a murine model. We compared N-acetylcysteine (NAC), a precursor of… CONTINUE READING