L-Dopa medication remediates cognitive inflexibility, but increases impulsivity in patients with Parkinson's disease.

@article{Cools2003LDopaMR,
  title={L-Dopa medication remediates cognitive inflexibility, but increases impulsivity in patients with Parkinson's disease.},
  author={Roshan Cools and Roger A. Barker and Barbara J. Sahakian and Trevor W. Robbins},
  journal={Neuropsychologia},
  year={2003},
  volume={41 11},
  pages={1431-41}
}
In the current study we investigated the role of dopamine in attentional and socio-emotional functioning by examining effects of withdrawing dopaminergic medication in patients with Parkinson's disease (PD). Patients "on" medication exhibited abnormal betting strategies on a task of decision-making, reflecting impulsive behaviour and/or delay aversion, whilst the same patients "off" medication exhibited abnormally increased switch costs when switching between two tasks, reflecting attentional… CONTINUE READING

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