L-Dopa Medication in Parkinson's Disease Restores Activity in the Motor Cortico-Striatal Loop but Does Not Modify the Cognitive Network

@inproceedings{Jubault2009LDopaMI,
  title={L-Dopa Medication in Parkinson's Disease Restores Activity in the Motor Cortico-Striatal Loop but Does Not Modify the Cognitive Network},
  author={Thomas Jubault and Laura Monetta and Antonio P. Strafella and Anne-Louise Lafontaine and Oury Monchi},
  booktitle={PloS one},
  year={2009}
}
BACKGROUND The goal of this study was to evaluate the effects of L-Dopa medication in Parkinson's disease (PD) on brain activation during the performance of a set-shifting task. Using fMRI, we have previously studied the patterns of activity observed in patients with PD after overnight removal of dopaminergic medication compared with control participants during the performance of different stages of the Wisconsin Card Sorting Task (WCST). The results revealed decreased cortical activity in the… CONTINUE READING