L-Chlorozotocin.

Abstract

L-Chlorozotocin (2-[[[2-chloroethyl)nitrosoamino]carbonyl]amino]-2-deoxy-L-glucose) was synthesized in seven steps from L-arabinose for comparison with chlorozotocin, which is the D enantiomorph and an antineoplastic agent with clinical potential. Purification of the intermediate 2-amino-2-deoxy-L-glucose as the Schiff's base formed with 4… (More)

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Cite this paper

@article{Johnston1979LChlorozotocin, title={L-Chlorozotocin.}, author={Thomas P. Johnston and G S McCaleb and Tanya R. Anderson and D S Murinson}, journal={Journal of medicinal chemistry}, year={1979}, volume={22 5}, pages={597-9} }