L-Carnitine dissimilation in the gastrointestinal tract of the rat.

  title={L-Carnitine dissimilation in the gastrointestinal tract of the rat.},
  author={Charles J. Rebouche and David L. Mack and P F Edmonson},
  volume={23 26},
Results of previous studies in this laboratory and others have suggested that L-carnitine is degraded in the gastrointestinal tract of the rat, perhaps by the action of indigenous flora. L-[methyl-14C]Carnitine was administered to rats either orally or intravenously in doses of 86 nmol or 124 mumol, and expired air, 48-h urine and fecal collections, and selected tissues at 48 h after isotope administration were examined for radiolabeled carnitine and metabolites. Urine and feces of rats… CONTINUE READING


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