L-Carnitine: therapeutic applications of a conditionally-essential amino acid.
@article{Kelly1998LCarnitineTA, title={L-Carnitine: therapeutic applications of a conditionally-essential amino acid.}, author={Gregory S. Kelly}, journal={Alternative medicine review : a journal of clinical therapeutic}, year={1998}, volume={3 5}, pages={ 345-60 } }
A trimethylated amino acid roughly similar in structure to choline, carnitine is a cofactor required for transformation of free long-chain fatty acids into acylcarnitines, and for their subsequent transport into the mitochondrial matrix, where they undergo beta-oxidation for cellular energy production. Mitochondrial fatty acid oxidation is the primary fuel source in heart and skeletal muscle, pointing to the relative importance of this nutrient for proper function in these tissues. Although L…
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