Kynurenine pathway enzymes in guinea pigs.


In some animals, the administration of repeated doses of tryptophan can cause death. It has been reported that guinea pig does not survive repeated doses of tryptophan, due to the absence of the hormonal induction mechanism of liver tryptophan 2,3-dioxygenase (TDO). Therefore, it was of interest to investigate if guinea pig is an animal model suitable for… (More)


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@article{Allegri2003KynureninePE, title={Kynurenine pathway enzymes in guinea pigs.}, author={Graziella Allegri and Carlo Virgilio Luigi Costa and Eugenio Ragazzi and Antonella Bertazzo and Monica Biasiolo}, journal={Advances in experimental medicine and biology}, year={2003}, volume={527}, pages={465-71} }