Kynurenine and neopterin levels in patients with rheumatoid arthritis and osteoporosis during drug treatment.

Abstract

The kynurenine pathway from tryptophan generates compounds which can act on glutamate receptors in peripheral tissues or modulate free radical activity. We have measured the concentrations of several of these compounds in the plasma of patients with rheumatoid arthritis (RA) and osteoporosis (OP) before treatment with drugs and then at monthly intervals for… (More)

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