Kynurenic Acid Metabolism in Various Types of Brain Pathology in HIV-1 Infected Patients

@inproceedings{Baran2012KynurenicAM,
  title={Kynurenic Acid Metabolism in Various Types of Brain Pathology in HIV-1 Infected Patients},
  author={Halina Baran and J. A. Hainfellner and Berthold Kepplinger},
  booktitle={International journal of tryptophan research : IJTR},
  year={2012}
}
Kynurenic acid, an intermediate metabolite of L-kynurenine, is a competitive antagonist of inotropic excitatory amino acid (EAA) receptors as well as a non competitive antagonist of 7 alpha nicotine cholinergic receptors and its involvement in memory deficit and cognition impairment has been suggested. Alterations of kynurenic acid metabolism in the brain after HIV-1 (human immunodeficiency virus type-1) infection have been demonstrated. The present study evaluates the biosynthetic machinery of… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-8 of 8 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 52 references

Similar Papers

Loading similar papers…