Kyanomycin, a complex of unusual anthracycline-phospholipid hybrids from Nonomuria species.

  title={Kyanomycin, a complex of unusual anthracycline-phospholipid hybrids from Nonomuria species.},
  author={C Pfefferle and Jens Breinholt and Carl Erik Olsen and Reiner M. Kroppenstedt and E M Wellington and Hanne G{\"u}rtler and H. P. Fiedler},
  journal={Journal of natural products},
  volume={63 3},
A blue secondary metabolite complex, named kyanomycin (2), in addition to epsilon-rhodomycinone (1), was detected in the mycelium extract of Nonomuria sp. NN 22303 by HPLC-diode array and HPLC-electrospray mass spectrometry screening. The chemical structures of the novel compounds were determined to be unusual anthracycline-phosphatidylethanolamine hybrids by spectroscopic and chemical degradation experiments. 
4 Citations

Enterobactin: the characteristic catecholate siderophore of Enterobacteriaceae is produced by Streptomyces species.(1).

In the course of a HPLC with diode array detection screening programme for detection of novel secondary metabolites, enterobactin, its biosynthetic precursor 2,3-dihydroxy-N-benzoylserine and its linear dimer and trimer condensation products were found to be produced by two Streptomyces strains besides the trihydroxamate-type siderophores desferri-ferrioxamine B and E.

Nature's palette: the search for natural blue colorants.

The scarcity of blue-colored metabolites in the natural world relative to metabolites of other colors is discussed, and structural trends common among natural blue compounds are identified.

Structure and function of “metalloantibiotics”

  • L. Ming
  • Chemistry, Biology
    Medicinal research reviews
  • 2003
Although most antibiotics do not need metal ions for their biological activities, there are a number of antibiotics that require metal ions to function properly, such as bleomycin, streptonigrin, and bacitracin, which are the title subjects of this review.