Kupffer cell activation by ambient air particulate matter exposure may exacerbate non-alcoholic fatty liver disease.

@article{Tan2009KupfferCA,
  title={Kupffer cell activation by ambient air particulate matter exposure may exacerbate non-alcoholic fatty liver disease.},
  author={Hui-Hui Tan and Maria Isabel Fiel and Qinghua Sun and Jinsheng Guo and Ronald E. Gordon and Lung-chi Chen and Scott L Friedman and Joseph A. Odin and Jorge Allina},
  journal={Journal of immunotoxicology},
  year={2009},
  volume={6 4},
  pages={
          266-75
        }
}
Owing to increased obesity, non-alcoholic fatty liver disease (NAFLD) is now the most prevalent liver disease in the United States. NAFLD is considered a component of metabolic syndrome, a cluster of disorders that also includes diabetes mellitus, dyslipidemia, arteriosclerosis, and hypertension. Exposure to ambient air particulate matter with aerodynamic diameters < 2.5 microm (PM(2.5)) is a risk factor for arteriosclerosis and lung disease, but its effect on NAFLD is unknown. PM(2.5) induces… CONTINUE READING
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