Ktenate nanoparticles (bdellosomes): a novel strategy for delivering drugs to parasites or tumours

@inproceedings{Flaig2005KtenateN,
  title={Ktenate nanoparticles (bdellosomes): a novel strategy for delivering drugs to parasites or tumours},
  author={Ruediger Marcus Flaig and Vera Rosenkranz and Michael Wink and Gert Fricker},
  year={2005}
}
Specific delivery of substances to distinct target cells may lead to new perspectives in diagnosis and therapy. We developed a drug delivery system based on nanoparticles made of polyvinyl alcohol grafted with polylactide side chains terminating in amino groups. These particles, termed “bdellosomes”, were loaded with substances of pharmacological interest, coated with polyethyleneglycol-3400 to evade immune reactions and linked to target-specific ligands, such as transferrin or anti-transferrin… CONTINUE READING