Krimpsiekte and acute cardiac glycoside poisoning in sheep caused by bufadienolides from the plant Kalanchoe lanceolata Forsk.

@article{Anderson1983KrimpsiekteAA,
  title={Krimpsiekte and acute cardiac glycoside poisoning in sheep caused by bufadienolides from the plant Kalanchoe lanceolata Forsk.},
  author={L3onald A Anderson and Rowina A Schultz and Johan P.R. Joubert and Leon Prozesky and T Stephanus Kellerman and Gerdinand L. Erasmus and J. S. Procos},
  journal={The Onderstepoort journal of veterinary research},
  year={1983},
  volume={50 4},
  pages={
          295-300
        }
}
Three toxic bufadienolides , one characterized as hellibrigenin 3-acetate, have been isolated from Kalanchoe lanceolata Forsk. Typical signs of cardiac glycoside poisoning, involving the gastro-intestinal, neuromuscular and cardiovascular systems, could be induced by drenching the milled plant to sheep. Such signs could also be induced by dosing the bufadienolides to sheep or by injecting them into both guinea-pigs (subcutaneously) and sheep (intravenously). The specific paretic syndrome… CONTINUE READING

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