Kraepelin and manic-depressive insanity: an historical perspective.

  title={Kraepelin and manic-depressive insanity: an historical perspective.},
  author={Francis M. Mondimore},
  journal={International review of psychiatry},
  volume={17 1},
Since the time of the ancient Greeks, physicians have recognized a certain relatedness between the mental states of depression and mania. In the mid-Nineteenth century, French alienists proposed a 'double' or 'circular' illness consisting of alternating depressed and manic episodes and at the beginning of the twentieth century, Emil Kraepelin introduced the term 'manic-depressive insanity.' Kraepelin's broad clinical experience resulted in compelling descriptions of the symptoms of mood… CONTINUE READING

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