Kraemer-Null Mutant MiceNTRArtery of p 75 Reduced Apoptosis and Increased Lesion Development in the Flow-Restricted Carotid

Apoptosis of neointimal smooth muscle cells is a well-recognized component of the pathogenesis of vascular lesions. In recent studies, we have identified the neurotrophin receptor, p75, as a mediator of apoptosis of neointimal smooth muscle cells. Neurotrophin ligands and p75 are selectively expressed in areas of atherosclerotic lesions with increased… CONTINUE READING