Krüppel-like factors in cancer progression: three fingers on the steering wheel

@inproceedings{Limame2014KrppellikeFI,
  title={Kr{\"u}ppel-like factors in cancer progression: three fingers on the steering wheel},
  author={Ridha Limame and Ken Op de Beeck and Filip Lardon and Olivier de Wever and Patrick Pauwels},
  booktitle={Oncotarget},
  year={2014}
}
Krüppel-like factors (KLFs) comprise a highly conserved family of zinc finger transcription factors, that are involved in a plethora of cellular processes, ranging from proliferation and apoptosis to differentiation, migration and pluripotency. During the last few years, evidence on their role and deregulation in different human cancers has been emerging. This review will discuss current knowledge on Krüppel-like transcription in the epithelial-mesenchymal transition (EMT), invasion and… CONTINUE READING

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