Krüppel-like factors 4 and 5: the yin and yang regulators of cellular proliferation

Abstract

ABSTRACTKrüppel-like factors (KLFs) are evolutionarily conserved zinc finger-containing transcription factors with diverse regulatory functions in cell growth, proliferation, differentiation, and embryogenesis. KLF4 and KLF5 are two closely related members of the KLF family that have a similar tissue distribution in embryos and adults. However, the two KLFs… (More)
DOI: 10.1038/sj.cr.7290271

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