Krüppel-like factor 5 mediates the transforming activity of oncogenic H-Ras

Abstract

Previous studies indicate that Krüppel-like factor 5 (KLF5), also known as intestinal-enriched Krüppel-like factor (IKLF), is a positive regulator of cell proliferation and gives rise to a transformed phenotype when overexpressed. Here we demonstrate that levels of KLF5 transcript and protein are significantly elevated in oncogenic H-Ras-transformed NIH3T3… (More)
DOI: 10.1038/sj.onc.1207397

8 Figures and Tables

Topics

  • Presentations referencing similar topics