Koch’s postulates and infectious proteins

@article{Walker2006KochsPA,
  title={Koch’s postulates and infectious proteins},
  author={L. Walker and H. Levine and M. Jucker},
  journal={Acta Neuropathologica},
  year={2006},
  volume={112},
  pages={1-4}
}
  • L. Walker, H. Levine, M. Jucker
  • Published 2006
  • Biology, Medicine
  • Acta Neuropathologica
  • Koch’s postulates were formulated in the late nineteenth century as guidelines for establishing that microbes cause specific diseases. Because the rules were developed for living agents—particularly bacteria—their applicability to inanimate pathogens such as viruses and infectious proteins has been problematic. The unorthodox mechanism by which prion diseases are transmitted, involving specific physicochemical characteristics of the protein as well as susceptibility traits of the host, has made… CONTINUE READING
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