Knowledge Enrichment Analysis for Human Tissue-Specific Genes Uncover New Biological Insights

@article{Gong2012KnowledgeEA,
  title={Knowledge Enrichment Analysis for Human Tissue-Specific Genes Uncover New Biological Insights},
  author={X. Gong and Hua Yu and Chun-Bai Yang and Yuan-Fang Li},
  journal={Journal of integrative bioinformatics},
  year={2012},
  volume={9 2},
  pages={
          194
        }
}
  • X. Gong, Hua Yu, +1 author Yuan-Fang Li
  • Published 2012
  • Biology, Computer Science, Medicine
  • Journal of integrative bioinformatics
The expression and regulation of genes in different tissues are fundamental questions to be answered in biology. Knowledge enrichment analysis for tissue specific (TS) and housekeeping (HK) genes may help identify their roles in biological process or diseases and gain new biological insights. In this paper, we performed the knowledge enrichment analysis for 17,343 genes in 84 human tissues using Gene Set Enrichment Analysis (GSEA) and Hypergeometric Analysis (HA) against three biological… Expand

References

SHOWING 1-10 OF 29 REFERENCES
TiSGeD: a database for tissue-specific genes
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
Annotating the human genome with Disease Ontology
Large-scale analysis of the human and mouse transcriptomes
  • A. Su, M. Cooke, +11 authors J. Hogenesch
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences of the United States of America
  • 2002
...
1
2
3
...