Knowledge‐based protein secondary structure assignment

  title={Knowledge‐based protein secondary structure assignment},
  author={Dmitrij Frishman and Patrick Argos},
  journal={Proteins: Structure},
We have developed an automatic algorithm STRIDE for protein secondary structure assignment from atomic coordinates based on the combined use of hydrogen bond energy and statistically derived backbone torsional angle information. Parameters of the pattern recognition procedure were optimized using designations provided by the crystallographers as a standard‐of‐truth. Comparison to the currently most widely used technique DSSP by Kabsch and Sander (Biopolymers 22:2577‐2637, 1983) shows that… 

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