Knowing one's place: a free-energy approach to pattern regulation

  title={Knowing one's place: a free-energy approach to pattern regulation},
  author={Karl J. Friston and Michael Levin and Biswa Sengupta and Giovanni Pezzulo},
  booktitle={Journal of the Royal Society, Interface},
Understanding how organisms establish their form during embryogenesis and regeneration represents a major knowledge gap in biological pattern formation. It has been recently suggested that morphogenesis could be understood in terms of cellular information processing and the ability of cell groups to model shape. Here, we offer a proof of principle that self-assembly is an emergent property of cells that share a common (genetic and epigenetic) model of organismal form. This behaviour is… CONTINUE READING
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