Knockout and overexpression of pyrroloquinoline quinone biosynthetic genes in Gluconobacter oxydans 621H.

@article{Hlscher2006KnockoutAO,
  title={Knockout and overexpression of pyrroloquinoline quinone biosynthetic genes in Gluconobacter oxydans 621H.},
  author={Tina H{\"o}lscher and Helmut G{\"o}risch},
  journal={Journal of bacteriology},
  year={2006},
  volume={188 21},
  pages={7668-76}
}
In Gluconobacter oxydans, pyrroloquinoline quinone (PQQ) serves as the cofactor for various membrane-bound dehydrogenases that oxidize sugars and alcohols in the periplasm. Proteins for the biosynthesis of PQQ are encoded by the pqqABCDE gene cluster. Our reverse transcription-PCR and promoter analysis data indicated that the pqqA promoter represents the only promoter within the pqqABCDE cluster of G. oxydans 621H. PQQ overproduction in G. oxydans was achieved by transformation with the plasmid… CONTINUE READING

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References

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The pyrroloquinoline quinone synthesis genes of Gluconobacter oxydans.

FEMS microbiology letters • 2000
View 7 Excerpts
Highly Influenced

A Gluconobacter oxydans mutant converting VOL

M. Elfari, S.-W. Ha, +5 authors H. Görisch
Appl. Microbiol. Biotechnol • 2005
View 1 Excerpt

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