Knockdown of zif268 in the Posterior Dorsolateral Striatum Does Not Enduringly Disrupt a Response Memory of a Rewarded T-Maze Task

@inproceedings{Cahill2018KnockdownOZ,
  title={Knockdown of zif268 in the Posterior Dorsolateral Striatum Does Not Enduringly Disrupt a Response Memory of a Rewarded T-Maze Task},
  author={Emma N. Cahill and George H. Vousden and Marc T J Exton-McGuinness and Ian R.C. Beh and Casey B. Swerner and Matej Macak and Sameera Abas and Cameron C. Cole and Brian Kelleher and Barry J. Everitt and Amy L Milton},
  booktitle={Neuroscience},
  year={2018}
}
Under certain conditions pavlovian memories undergo reconsolidation, whereby the reactivated memory can be disrupted by manipulations such as knockdown of zif268. For instrumental memories, reconsolidation disruption is less well established. Our previous, preliminary data identified that there was an increase in Zif268 in the posterior dorsolateral striatum (pDLS) after expression of an instrumental habit-like 'response' memory, but not an instrumental goal-directed 'place' memory on a T-maze… CONTINUE READING
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