Knockdown of transient receptor potential canonical-1 reduces the proliferation and migration of endothelial progenitor cells.

@article{Kuang2012KnockdownOT,
  title={Knockdown of transient receptor potential canonical-1 reduces the proliferation and migration of endothelial progenitor cells.},
  author={Chun-yan Kuang and Yonghao Yu and Kui Wang and De-hui Qian and Meng-yang Den and Lan Huang},
  journal={Stem cells and development},
  year={2012},
  volume={21 3},
  pages={487-96}
}
Endothelial progenitor cells (EPCs) play an important role in accelerating endothelial repair after vascular injury. The proliferation and migration of EPCs is a critical first step in restoring endothelial. However, mechanisms for modulating EPC proliferation and migration are still being elucidated. Our previous study found that transient receptor potential canonical-1 (TRPC1) is involved in regulating store-operated Ca(2+) entry in EPCs through stromal interaction molecule 1. Therefore, in… CONTINUE READING

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Roles of store-operated Ca2+ channels in regulating cell cycling and migration of human cardiac c-kit+ progenitor cells.

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Store-operated calcium channels.

Physiological reviews • 2005
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