Knockdown of PTTG1 inhibits the growth and invasion of lung adenocarcinoma cells through regulation of TGFB1/SMAD3 signaling.

Abstract

Increased expression of pituitary tumor-transforming gene 1 (PTTG1) is expressed in many tumors and regulates tumor growth and progression. However, the precise function of PTTG1 in the tumorigenesis of lung adenocarcinoma (LAC) is not defined yet. Here, we examined the expression of PTTG1 in human LAC tissues by immunohistochemical assay using a tissue… (More)
DOI: 10.1177/0306419015572073

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@article{Li2015KnockdownOP, title={Knockdown of PTTG1 inhibits the growth and invasion of lung adenocarcinoma cells through regulation of TGFB1/SMAD3 signaling.}, author={W-H Li and L. Chang and Y-X Xia and Liping Wang and Y-Y Liu and Y-H. Wang and Z. Jiang and J. Xiao and Z-R Wang}, journal={International journal of immunopathology and pharmacology}, year={2015}, volume={28 1}, pages={45-52} }