Knockdown of MAPK14 inhibits the proliferation and migration of clear cell renal cell carcinoma by downregulating the expression of CDC25B

@article{Liu2019KnockdownOM,
  title={Knockdown of MAPK14 inhibits the proliferation and migration of clear cell renal cell carcinoma by downregulating the expression of CDC25B},
  author={Junlong Liu and Xiuyue Yu and H. Yu and Bitian Liu and Z. Zhang and C. Kong and Z. Li},
  journal={Cancer Medicine},
  year={2019},
  volume={9},
  pages={1183 - 1195}
}
  • Junlong Liu, Xiuyue Yu, +4 authors Z. Li
  • Published 2019
  • Chemistry, Medicine
  • Cancer Medicine
  • Mitogen‐activated protein kinase 14 (MAPK14), which plays an important role in DNA damage and repair, is activated by various environmental stress and proinflammatory cytokines. It is highly active in a variety of tumors, acting as a tumor promoter or suppressor, but its role in clear cell renal cell carcinoma (ccRCC) has not been elucidated. Cell division cycle 25B (CDC25B) is involved in cell cycle regulation and is highly expressed in many malignant tumors. The transcription levels of MAPK14… CONTINUE READING
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