Knockdown of IG20 gene expression renders thyroid cancer cells susceptible to apoptosis.

Abstract

AIM The aim of the study was to investigate the expression and function of the IG20 gene in thyroid cancer cell survival, proliferation, and apoptosis. METHODS We determined the expression levels of the major isoforms of IG20 by quantitative RT-PCR in normal and thyroid tumor tissues/cell lines. We evaluated the functional consequence of IG20 knockdown in… (More)
DOI: 10.1210/jc.2008-2378

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