Knockdown of GPR137 by RNAi inhibits pancreatic cancer cell growth and induces apoptosis.


G-protein-coupled receptors (GPCRs), the largest family of cell-surface molecules involved in a number of biological and pathological processes, have recently emerged as key players in carcinogenesis and cancer progression. Orphan G protein-coupled receptors (oGPCRs) are a group of proteins lacking endogenous ligands. GPR137, one of the novel oGPCR genes… (More)
DOI: 10.1002/bab.1326


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