Knockdown of CDKN1C (p57kip2) and PHLDA2 Results in Developmental Changes in Bovine Pre-implantation Embryos

@inproceedings{Driver2013KnockdownOC,
  title={Knockdown of CDKN1C (p57kip2) and PHLDA2 Results in Developmental Changes in Bovine Pre-implantation Embryos},
  author={Ashley M. Driver and Wen Xu Huang and Jenna Kropp and Francisco Pe{\~n}agaricano and Hasan Khatib},
  booktitle={PloS one},
  year={2013}
}
Imprinted genes have been implicated in early embryonic, placental, and neonatal development and alterations in expression levels of these genes can lead to growth abnormalities and embryonic lethality. However, little is known about the functions of bovine imprinted genes during the pre-implantation period. Therefore, the objective of this study was to assess the influence of altered expression of imprinted genes on developmental progress of embryos using small interfering RNA (siRNA… CONTINUE READING

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