Kisspeptin in the medial amygdala and sexual behavior in male rats

  title={Kisspeptin in the medial amygdala and sexual behavior in male rats},
  author={Rebecca Gresham and Shengyun Li and Daniel A Adekunbi and Minghan Hu and Xiao Feng Li and Kevin T. O’Byrne},
  booktitle={Neuroscience Letters},
The medial amygdala (MeA) is crucial for sexual behavior; kisspeptin (Kiss1) also plays a role in sexual function. Kisspeptin receptor (Kiss1r) knockout mice display no sexual behavior. Recently Kiss1 and Kiss1r have been discovered in the posterodorsal subnucleus of the medial amygdala (MePD). We hypothesised that Kiss1 in the MePD may have an influence on male sexual behavior. To test this we bilaterally cannulated the MePD and infused kisspeptin-10 in male rats. This caused the rats to have… CONTINUE READING


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Discovery of potent kisspeptin antagonists delineate physiological mechanisms of gonadotropin regulation.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 2009

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