Kisspeptin immunoreactive cells of the ovine preoptic area and arcuate nucleus co-express estrogen receptor alpha.

@article{Franceschini2006KisspeptinIC,
  title={Kisspeptin immunoreactive cells of the ovine preoptic area and arcuate nucleus co-express estrogen receptor alpha.},
  author={Isabelle Franceschini and Didier Lomet and Marilyn Cateau and Georges Delsol and Yves Tillet and Alain Caraty},
  journal={Neuroscience letters},
  year={2006},
  volume={401 3},
  pages={225-30}
}
Kisspeptins are peptide ligands of the G protein-coupled receptor GPR54, recently shown to be essential to reproductive function. We have raised specific rabbit antisera against a highly conserved 10 amino acid-amidated peptide (kp10) common to all kisspeptin isoforms isolated so far and mapped the distribution of kp10-immunoreactive (ir) cells in the ovine hypothalamus. Kp10-ir cells were predominant in the caudal arcuate nucleus, the dorsomedial nucleus and the medial preoptic area. Numerous… CONTINUE READING
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