Kinin B1 receptors: key G-protein-coupled receptors and their role in inflammatory and painful processes.

@article{Calixto2004KininBR,
  title={Kinin B1 receptors: key G-protein-coupled receptors and their role in inflammatory and painful processes.},
  author={Jo{\~a}o Batista Calixto and Rodrigo Medeiros and Elizabeth Soares Fernandes and Juliano Ferreira and Daniela de Almeida Cabrini and Maria Martha Campos},
  journal={British journal of pharmacology},
  year={2004},
  volume={143 7},
  pages={803-18}
}
Kinins are a family of peptides implicated in several pathophysiological events. Most of their effects are likely mediated by the activation of two G-protein-coupled receptors: B(1) and B(2). Whereas B(2) receptors are constitutive entities, B(1) receptors behave as key inducible molecules that may be upregulated under some special circumstances. In this context, several recent reports have investigated the importance of B(1) receptor activation in certain disease models. Furthermore, research… CONTINUE READING
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