Kinetochore motors drive congression of peripheral polar chromosomes by overcoming random arm-ejection forces

@article{Barisic2014KinetochoreMD,
  title={Kinetochore motors drive congression of peripheral polar chromosomes by overcoming random arm-ejection forces},
  author={Marin Barisic and Paulo Aguiar and Stephan Geley and Helder Maiato},
  journal={Nature Cell Biology},
  year={2014},
  volume={16},
  pages={1249-1256}
}
Accurate chromosome segregation during cell division in metazoans relies on proper chromosome congression at the equator. Chromosome congression is achieved after bi-orientation to both spindle poles shortly after nuclear envelope breakdown, or by the coordinated action of motor proteins that slide misaligned chromosomes along pre-existing spindle microtubules. These proteins include the minus-end-directed kinetochore motor dynein, and the plus-end-directed motors CENP-E at kinetochores and… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 20 times over the past 90 days. VIEW TWEETS

Citations

Publications citing this paper.
Showing 1-10 of 29 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 45 references

Similar Papers

Loading similar papers…