Kinetochore microtubules in PTK cells

  title={Kinetochore microtubules in PTK cells},
  author={Katharine L. McDonald and Eileen O'Toole and David N. Mastronarde and J Richard McIntosh},
  journal={The Journal of Cell Biology},
  pages={369 - 383}
We have analyzed the fine structure of 10 chromosomal fibers from mitotic spindles of PtK1 cells in metaphase and anaphase, using electron microscopy of serial thin sections and computer image processing to follow the trajectories of the component microtubules (MTs) in three dimensions. Most of the kinetochore MTs ran from their kinetochore to the vicinity of the pole, retaining a clustered arrangement over their entire length. This MT bundle was invaded by large numbers of other MTs that were… CONTINUE READING
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Publications referenced by this paper.
Showing 1-10 of 43 references

Computer-based tools for morphometric analysis of mitotic spindles and other microtubule systems

K McDonald, D. Mastronarde, +3 authors Mclntosh
View 4 Excerpts
Highly Influenced

Motor proteins in cell division.

Trends in cell biology • 1991
View 1 Excerpt

Kinetochores capture

Hayden, H J., S. S. Bowser, C. L. Rieder
View 2 Excerpts

Mitotic spindle, ultrastructure and design

K. L. McDonald
Mitosis: • 1989
View 2 Excerpts

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