Kinetics study of endogenous heat shock protein 70 expression.

  title={Kinetics study of endogenous heat shock protein 70 expression.},
  author={Sihong Wang and Kenneth R. Diller and Shanti J. Aggarwal},
  journal={Journal of biomechanical engineering},
  volume={125 6},
The purpose of this study was to determine the kinetics of HSP70 expression in response to mild thermal stress. The rationale is to produce a basis for design of optimal heating methods to induce HSP70 expression for preconditioning in cardiac surgery. Bovine aortic endothelial cells were heated at 42 degrees C for 0.5 to 5 hours followed by 37 degrees C recovery for 1 to 48 hours. Quantitative analysis of western blot results showed HSP70 expression kinetics is a coupled function of heating… CONTINUE READING