Kinetics of water diffusion across phospholipid membranes. 1H- and 17O-NMR relaxation studies.

Abstract

Nuclear relaxation measurements of 1H and 17O of water have been applied to study the kinetics of water diffusion across vesicular lipid membranes. Differentiation between the intra- and extravesicular media was achieved by entrapping Mn2+ inside the vesicles. The water permeability of egg phosphatidylcholine vesicles was found to be 2.9 x 10(-3) cm/s at 25… (More)

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