Kinetics of water diffusion across phospholipid membranes. 1H- and 17O-NMR relaxation studies.


Nuclear relaxation measurements of 1H and 17O of water have been applied to study the kinetics of water diffusion across vesicular lipid membranes. Differentiation between the intra- and extravesicular media was achieved by entrapping Mn2+ inside the vesicles. The water permeability of egg phosphatidylcholine vesicles was found to be 2.9 x 10(-3) cm/s at 25… (More)


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