Kinetics of viral loads and risk of hepatitis B virus reactivation in hepatitis B core antibody-positive rheumatoid arthritis patients undergoing anti-tumour necrosis factor alpha therapy.

@article{Lan2011KineticsOV,
  title={Kinetics of viral loads and risk of hepatitis B virus reactivation in hepatitis B core antibody-positive rheumatoid arthritis patients undergoing anti-tumour necrosis factor alpha therapy.},
  author={Joung-Liang Lan and Yi-Ming Chen and Tsu-Yi Hsieh and Yi-Hsing Chen and Chia-Wei Hsieh and Der-Yuan Chen and Sheng-Shun Yang},
  journal={Annals of the rheumatic diseases},
  year={2011},
  volume={70 10},
  pages={1719-25}
}
OBJECTIVE To investigate the kinetics of hepatitis B virus (HBV) viral loads and HBV reactivation in rheumatoid arthritis (RA) patients undergoing therapy with tumour necrosis factor alpha (TNFα) inhibitors. METHODS The authors investigated the virological, serological and biochemical evidence of HBV reactivation in 88 RA patients receiving anti-TNFα therapy. Levels of HBV surface (HBs) antigen (Ag), anti-HBV core (HBc)-IgG and anti-HBs antibody (Ab) were detected by electrochemiluminescence… CONTINUE READING
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