Kinetics of transplant arteriosclerosis in MHC-Class I mismatched and fully allogeneic mouse aortic allografts.

@article{Ensminger2002KineticsOT,
  title={Kinetics of transplant arteriosclerosis in MHC-Class I mismatched and fully allogeneic mouse aortic allografts.},
  author={Stephan M. Ensminger and Bernd M. Spriewald and Oliver Witzke and Karen Morrison and Octavio E. Pajaro and Peter J. Morris and Marlene L. Rose and Kathryn J. Wood},
  journal={Transplantation},
  year={2002},
  volume={73 7},
  pages={1068-74}
}
INTRODUCTION Transplant arteriosclerosis is still the major complication for long-term allograft survival in clinical transplantation. The aim of our study was to investigate the impact of MHC disparity on the kinetics of the development of transplant arteriosclerosis. METHODS MHC-class I mismatched CBK (H2k+Kb) or fully allogeneic C57BL/10 (H2b) aortic allografts were transplanted into CBA.CA (H2k) recipients; syngeneic grafts were used as controls. Aortic grafts were analyzed on days 7, 14… CONTINUE READING
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