Kinetics of thymocyte developmental process in fetal and neonatal mice

@article{Xiao2003KineticsOT,
  title={Kinetics of thymocyte developmental process in fetal and neonatal mice},
  author={S Y Xiao and Yan Li and Wei Chen},
  journal={Cell Research},
  year={2003},
  volume={13},
  pages={265-273}
}
ABSTRACTKinetics of thymocyte development in vivo during embryogenesis was pursued. The early development of thymocytes in the fetal and neonatal BALB/c mice was discontinuous, with four waves of cell proliferation occurring at fetal day (Fd) 14 to 17, Fd 18 to day (D) 1 after birth, D 2 to D 5 and D6 thereafter. The first three proliferation waves coincided with the generation of CD4hiCD8hi (DP), TCR+CD4hiCD8−/lo (CD4 SP), and TCR+CD4−/loCD8int/hi (CD8 SP) thymocytes, respectively. The… CONTINUE READING
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Multiple routes for late intrathymic precursors to generate CD4CD8 thymocytes. Advances in molecular and cell biology

P Hugo, HT Petrie
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