Kinetics of the release of the mitochondrial inhibitor protein. Correlation with synthesis and hydrolysis of ATP.

@article{Lippe1988KineticsOT,
  title={Kinetics of the release of the mitochondrial inhibitor protein. Correlation with synthesis and hydrolysis of ATP.},
  author={Giovanna Lippe and Maria Catia Sorgato and David A Harris},
  journal={Biochimica et biophysica acta},
  year={1988},
  volume={933 1},
  pages={
          1-11
        }
}
(1) The kinetics of the release of the mitochondrial inhibitor protein (IF1) is studied in bovine heart submitochondrial vesicles supplemented with 125I-labelled IF1, using a method for rapidly 'freezing' the state of F1-IF1 interaction. It is shown that generation of a protonmotive force leads to release of IF1 from F1 into solution, following an exponential process. (2) In one set of experiments the rate of IF1 release, in IF1 supplemented vesicles generating a protonmotive force, is… CONTINUE READING
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