Kinetics of the inflammatory response following intramuscular injection of aluminum adjuvant.

  title={Kinetics of the inflammatory response following intramuscular injection of aluminum adjuvant.},
  author={Fangjia Lu and Harm HogenEsch},
  volume={31 37},
Aluminum-containing adjuvants are widely used in human and veterinary vaccines, but their mechanism of action is not well understood. Recent evidence suggests an important role for inflammation in the immune response to aluminum-adjuvanted vaccines. To better understand this process, vaccines with aluminum adjuvant were injected into naïve or previously immunized mice and the injection sites were characterized for the corresponding primary and secondary inflammatory response at different time… CONTINUE READING
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