Kinetics of removal of intravenous testosterone pulses in normal men.

@article{Veldhuis2010KineticsOR,
  title={Kinetics of removal of intravenous testosterone pulses in normal men.},
  author={Johannes D. Veldhuis and Daniel M. Keenan and Peter Y Liu and Paul Y. Takahashi},
  journal={European journal of endocrinology},
  year={2010},
  volume={162 4},
  pages={787-94}
}
BACKGROUND Testosterone is secreted into the bloodstream episodically, putatively distributing into total, bioavailable (bio) nonsex hormone-binding globulin (nonSHBG-bound), and free testosterone moieties. The kinetics of total, bio, and free testosterone pulses are unknown. Design Adrenal and gonadal steroidogenesis was blocked pharmacologically, glucocorticoid was replaced, and testosterone was infused in pulses in four distinct doses in 14 healthy men under two different paradigms (a total… CONTINUE READING

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