Kinetics of protein binding in solid-phase immunoassays: theory.

@article{Klenin2005KineticsOP,
  title={Kinetics of protein binding in solid-phase immunoassays: theory.},
  author={K. Klenin and W. Kusnezow and J. Langowski},
  journal={The Journal of chemical physics},
  year={2005},
  volume={122 21},
  pages={
          214715
        }
}
In a solid-phase immunoassay, binding between an antigen and its specific antibody takes place at the boundary of a liquid and a solid phase. One of the reactants (receptor) is immobilized on a surface. The other reactant (ligand) is initially free in solution. We present a theory describing the kinetics of immunochemical reaction in such a system. A single essential restriction of the theory is the assumption that the reaction conditions are uniform along the binding surface. In general, the… Expand
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