Kinetics of lymphokine production by lymphocytes from elderly humans.


Production in vitro of the lymphokine leukocyte migration inhibition factor (LMIF) was studied for elderly as compared to young human subjects over an 8-day period of culture. When stimulated by either the antigen streptokinase/streptodornase (SK/SD) or the mitogen concanavalin A (Con A), the peak of LMIF production was retarded in cultures of lymphocytes… (More)


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