Kinetics of human alcohol dehydrogenase with ring-oxidized retinoids: effect of Tween 80.

Abstract

Human alcohol dehydrogenases (ADH1 and ADH4) actively use retinoids oxidized at the cyclohexenyl ring (4-oxo-, 4-hydroxy-, and 3,4-didehydro-retinoids), which are functional compounds in several cells and tissues (i.e., in human skin). Remarkably, activities with 4-oxo-retinal and 4-hydroxy-retinol (kcat = 2050 min(-1) for ADH4) are the highest among… (More)

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@article{Martras2004KineticsOH, title={Kinetics of human alcohol dehydrogenase with ring-oxidized retinoids: effect of Tween 80.}, author={S{\'i}lvia Martras and Rosana {\'A}lvarez and Oriol Gallego and Marta Dom{\'i}nguez and {\'A}ngel R de Lera and Jaume Farr{\'e}s and Xavier Par{\'e}s}, journal={Archives of biochemistry and biophysics}, year={2004}, volume={430 2}, pages={210-7} }