Kinetics of delayed-type hypersensitivity to tuberculin induced by bacille Calmette-Guérin vaccination in northern Malawi.

  title={Kinetics of delayed-type hypersensitivity to tuberculin induced by bacille Calmette-Gu{\'e}rin vaccination in northern Malawi.},
  author={Sian Floyd and Jorg M P{\"o}nnighaus and Lyn Bliss and Prince Nkhosa and Lifted Sichali and Glyn K Msiska and Paul E. M. Fine},
  journal={The Journal of infectious diseases},
  volume={186 6},
During 1986-1989, a bacille Calmette-Guérin (BCG) vaccine trial was carried out in northern Malawi. The effects of age, sex, and prevaccination delayed-type hypersensitivity (DTH) on the time course of the DTH response over 1-36 months after vaccination were studied in 2418 persons. DTH response increased rapidly, to peak at 31-90 days after vaccination, when most persons had a measurable response. This was followed by a marked decline by 181-365 days, particularly in those <15 years old at… CONTINUE READING

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Publications referenced by this paper.
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Tuberculin conversion after BCG vaccination: comparison by gestation and by age at immunization in Myanmar.

Transactions of the Royal Society of Tropical Medicine and Hygiene • 2000
View 2 Excerpts

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Clinical infectious diseases : an official publication of the Infectious Diseases Society of America • 2000

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The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease • 1999
View 3 Excerpts

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